RadVault Knowledge Base Index
Technique (3 pages)
| Page | Description |
|---|---|
| Dynamic Contrast Enhanced MRI | Foundation of breast MRI; DCE principles, timing, fat removal |
| Abbreviated MRI | Short protocol (<10 min); screening applications |
| Diffusion Weighted Imaging | Non-contrast DWI; ADC; not yet formal BI-RADS |
Overviews (1 page)
| Page | Description |
|---|---|
| Breast MRI Lexicon Overview | Master map-of-content; v2025 changes summary; benign combination rule |
Findings (8 pages)
| Page | Description |
|---|---|
| Fibroglandular Tissue | FGT categories; MRI vs mammographic density distinction |
| Background Parenchymal Enhancement | BPE definition, levels, symmetry, clinical significance |
| Masses | Mass definition; all descriptor categories; <2% rule; v2025 changes |
| Non-Mass Enhancement | NME definition; distribution and internal enhancement pattern categories |
| Lymph Nodes | Intramammary, axillary, internal mammary; normal vs abnormal; v2025 separate category |
| Associated Features | 8 features: nipple, skin, pectoralis, chest wall, peritumoral edema |
| Other Findings Typically Benign | 9 benign findings: cysts, fat necrosis, hamartoma, etc. |
| Implants and Augmentation | Location, material, integrity, rupture signs, BIA-ALCL |
Descriptors — FGT (4 pages)
| Page | Description |
|---|---|
| FGT — Almost Entirely Fatty | Category A |
| FGT — Scattered Fibroglandular Tissue | Category B |
| FGT — Heterogeneous Fibroglandular Tissue | Category C |
| FGT — Extreme Fibroglandular Tissue | Category D |
Descriptors — BPE (4 pages)
| Page | Description |
|---|---|
| BPE — Minimal | Includes no enhancement |
| BPE — Mild | Small amount of parenchymal enhancement |
| BPE — Moderate | Substantial parenchymal enhancement |
| BPE — Marked | Extensive parenchymal enhancement |
Descriptors — Mass Shape (4 pages)
| Page | Description |
|---|---|
| Mass Shape — Oval | Elliptical, no undulations; benign-favoring |
| Mass Shape — Lobulated | One or more indentations; v2025: reintroduced separate category |
| Mass Shape — Round | Spherical, equal diameters |
| Mass Shape — Irregular | Acute-angle protrusions; most suspicious shape |
Descriptors — Mass Margin (3 pages)
| Page | Description |
|---|---|
| Mass Margin — Circumscribed | Entire margin smooth/sharp; strict MRI definition |
| Mass Margin — Indistinct | Uneven, non-spiculated; v2025: replaces “irregular margin” |
| Mass Margin — Spiculated | Radiating lines; most suspicious margin |
Descriptors — Mass Internal Enhancement (4 pages)
| Page | Description |
|---|---|
| Mass Enhancement — Homogeneous | Confluent uniform enhancement |
| Mass Enhancement — Dark Internal Septations | Non-enhancing lines; fibroadenoma-suggestive |
| Mass Enhancement — Heterogeneous | Varied, non-uniform enhancement |
| Mass Enhancement — Thick Rim Enhancement | Peripheral thick rim; v2025: renamed from “rim enhancement” |
Descriptors — Mass T2 Signal (2 pages)
| Page | Description |
|---|---|
| Mass T2 Signal — Hyperintense | Lymph node bright; key benign-combination feature |
| Mass T2 Signal — Not Hyperintense | Not lymph node bright; most carcinomas |
Descriptors — Enhancement Kinetics (1 page)
| Page | Description |
|---|---|
| Enhancement Kinetics | Early phase (slow/medium/fast); delayed phase (persistent/plateau/washout) |
Descriptors — NME Distribution (5 pages)
| Page | Description |
|---|---|
| NME Distribution — Diffuse | 2+ quadrants; can be malignant |
| NME Distribution — Regional | >1 quadrant, not diffuse, not ductal |
| NME Distribution — Focal | <1 quadrant, not segmental/linear; least suspicious |
| NME Distribution — Linear | Line/branch pattern; suspicious — ductal |
| NME Distribution — Segmental | Cone/triangle, apex toward nipple; suspicious — ductal/segmental |
Descriptors — NME Internal Enhancement (4 pages)
| Page | Description |
|---|---|
| NME Enhancement — Homogeneous | Uniform NME enhancement |
| NME Enhancement — Heterogeneous | Varied NME enhancement |
| NME Enhancement — Clumped | Cobblestone-like grouped foci; suspicious |
| NME Enhancement — Clustered Ring | Clustered hollow ring foci; suspicious; high-grade DCIS |
Descriptors — Lymph Nodes (3 pages)
| Page | Description |
|---|---|
| Lymph Node — Intramammary | Within breast; no size threshold; compare to priors |
| Lymph Node — Axillary | Levels I-III; subjective asymmetry key; 3 mm rule NOT applicable |
| Lymph Node — Internal Mammary | Normal up to 9-10 mm in screening; >=5 mm suspicious with cancer |
Descriptors — Associated Features (8 pages)
| Page | Description |
|---|---|
| Associated Feature — Nipple Retraction | Pulled in; distinguish from inversion |
| Associated Feature — Nipple Involvement | Malignant enhancement contiguous with nipple; Paget disease |
| Associated Feature — Skin Retraction | Skin pulled in; benign if stable/post-surgical |
| Associated Feature — Skin Thickening | > 2 mm; focal or diffuse |
| Associated Feature — Skin Involvement | Definitive skin enhancement; staging T4b/T4d |
| Associated Feature — Pectoralis Muscle Involvement | NOT chest wall; distinct staging |
| Associated Feature — Chest Wall Involvement | Intercostal/serratus/ribs = T4a |
| Associated Feature — Peritumoral Edema | v2025 new; T2 bright around tumor; LN metastases risk |
Descriptors — Other Findings Typically Benign (9 pages)
| Page | Description |
|---|---|
| Other Finding — High T1 Duct Signal | Blood/protein in ducts; benign without ductal enhancement |
| Other Finding — Cysts | T2 bright; thin peri-cystic enhancement is benign |
| Other Finding — Postoperative Collections | Hematoma/seroma; thin peripheral enhancement benign |
| Other Finding — Post-Therapy Skin and Trabecular Thickening | After surgery/radiation |
| Other Finding — Non-Enhancing Mass | Benign solid mass (exception: post-NAC malignancy) |
| Other Finding — Signal Void | Metallic clip/foreign body artifact |
| Other Finding — Fat Necrosis | Internal fat signal diagnostic; variable enhancement |
| Other Finding — Hamartoma | Fat + FGT in pseudocapsule; enhanced FGT = benign |
| Other Finding — Enhancing Skin Lesions | Moles, keloids; usually not reported |
Descriptors — Implants (5 pages)
| Page | Description |
|---|---|
| Implant — Radial Folds | Normal infolding; NOT rupture |
| Implant — Subcapsular Line Sign | Intracapsular rupture |
| Implant — Keyhole Sign | Intracapsular rupture; silicone in radial fold |
| Implant — Linguine Sign | Advanced intracapsular rupture; pathognomonic |
| Implant — Water Droplets | Can occur in intact or ruptured implants |
Assessment (1 page)
| Page | Description |
|---|---|
| BI-RADS Assessment Categories | Categories 0-6; management; hierarchy 5>4>0>6>3>2/1; v2025 changes |
Guidance (2 pages)
| Page | Description |
|---|---|
| MRI Report Organization | 8 required components; structured indications (v2025 new) |
| v2025 Major Updates | Summary of all lexicon, reporting, and guidance changes |
Location (1 page)
| Page | Description |
|---|---|
| Location of Finding | Clock face, depth, distance from nipple; whole numbers only |
DDx Pages (5 pages)
| Page | Description |
|---|---|
| Thick Rim Enhancement DDx | IDC vs abscess vs fat necrosis |
| T2 Hyperintense Mass DDx | Fibroadenoma vs mucinous carcinoma vs cyst |
| NME Distribution DDx | Differential by distribution type; distribution x pattern matrix |
| Oval Circumscribed Mass DDx | Fibroadenoma vs lymph node vs mucinous carcinoma |
| Breast Imaging Differential Diagnoses | Comprehensive multimodality DDx — calcs, masses, AD, NME, LN, BI-RADS 5 mimics |
Breast Imaging — Technique (9 pages)
| Page | Description |
|---|---|
| Breast Cancer Staging | TNM AJCC 8th; T/N/M categories; 5-year survival; multifocal vs multicentric |
| Breast Cancer Treatment | SLNB, radiation, systemic therapy, margins, anticoagulation |
| Post-Operative Breast | Lumpectomy changes, RT timeline, recurrence detection |
| Breast Reconstruction | TRAM vs DIEP, pedicled vs free flaps, ADM |
| Breast Implants — Multimodality | Implant types, rupture signs all modalities, BIA-ALCL, FDA guidelines |
| Biopsy Technique | US/stereotactic/MRI-guided biopsy, clips, anticoagulation |
| Breast MRI Extra-Mammary Findings | Distant mets, lymph nodes, chest wall, staging |
| Breast Ultrasound Technique | Screening, ACRIN 6666, malignant features, spatial compound |
| Key Clinical Trials | Z0011, Z1071, ACRIN 6666, Choosing Wisely |
Breast Imaging — Special Populations (2 pages)
| Page | Description |
|---|---|
| Pregnancy and Lactation Imaging | Radiation safety, gadolinium, SLNB, rusty pipe syndrome, pediatric |
| Artificial Intelligence in Breast Imaging | AI concepts, performance, patient acceptance |
Breast Imaging — Findings (2 pages)
| Page | Description |
|---|---|
| BIA-ALCL | BIA-ALCL pathogenesis, imaging, staging, treatment, prognosis |
Page Count Summary
| Category | Count |
|---|---|
| Technique (MRI) | 3 |
| Technique (Breast Imaging) | 9 |
| Special Populations | 2 |
| Overview | 1 |
| Finding | 9 |
| Descriptor | 56 |
| Assessment | 1 |
| Guidance | 2 |
| Location | 1 |
| DDx | 5 |
| Total | 89 |
Rectal Cancer — Technique (1 page)
| Page | Description |
|---|---|
| High Resolution Rectal MRI | MRI technique for rectal cancer staging; structured reporting |
Rectal Cancer — Overviews (1 page)
| Page | Description |
|---|---|
| Rectal Cancer Staging Overview | Master map-of-content; 8 key controversies; evolving treatment paradigm |
Rectal Cancer — Findings (3 pages)
| Page | Description |
|---|---|
| Rectal Anatomy for Staging | Anal canal definitions; rectum definition; vascular/lymphatic drainage |
| Mesorectal Fascia | MRF anatomy; involvement criteria; 1 mm cutoff; MRI performance |
| Circumferential Resection Margin | CRM vs MRF distinction; surgical variability |
Rectal Cancer — Descriptors (7 pages)
| Page | Description |
|---|---|
| Anterior Peritoneal Reflection | APR seagull sign; upper vs lower rectum; peritoneal investment |
| Sigmoid Takeoff | STO imaging landmark; validation; pitfalls |
| Rectal Cancer T Staging | AJCC 8th edition T stages; sphincter controversy; MRF and T stage |
| Extramural Vascular Invasion | EMVI MRI appearance; prognostic significance; MRF involvement |
| Tumor Deposits | Definition; comet tail sign; distinction from lymph nodes |
| Lateral Pelvic Lymph Nodes | LPLN compartments; size criteria; pre/post-nCRT thresholds |
| Sphincter Complex | Internal/external sphincter; puborectalis; surgical anal canal |
Rectal Cancer — Guidance (1 page)
| Page | Description |
|---|---|
| Rectal Cancer Neoadjuvant Therapy Decision | Upper vs lower rectum management; anatomy over stage paradigm |
Page Count Summary
| Category | Count |
|---|---|
| Technique | 4 |
| Overview | 2 |
| Finding | 11 |
| Descriptor | 63 |
| Assessment | 1 |
| Guidance | 3 |
| Location | 1 |
| DDx | 4 |
| Total | 89 |
Last updated: 2026-04-14 — All of Breast Imaging (1).pdf ingest (88 pages, 13 new wiki pages, 93 new cards)
RECIST — Assessment (1 page)
| Page | Description |
|---|---|
| RECIST 1.1 Overview | Master assessment page; CR/PR/SD/PD; master response table; endpoints |
RECIST — Descriptors (5 pages)
| Page | Description |
|---|---|
| Measurable Disease | Measurable vs non-measurable; thresholds; nodal size cutoffs |
| Target Lesions | Selection (max 5/2 per org); sum of diameters; tracking rules |
| Non-target Lesions | Qualitative tracking; unequivocal progression; non-target-only patients |
| New Lesions | Unequivocal standard; PET rules; unscanned locations; reappearance rule |
| Nadir Concept | Nadir vs baseline; PD calculation; continuing PR |
RECIST — Comparison (1 page)
| Page | Description |
|---|---|
| RECIST v1.0 vs v1.1 | All 7 major changes between versions |
RECIST — Guidance (1 page)
| Page | Description |
|---|---|
| Alternative Response Criteria | Choi (GIST), iRECIST (immunotherapy), mRECIST (HCC), Lugano (lymphoma) |