Breast Implants — Multimodality Assessment

Implant Types

Materials

TypeKey Features
Silicone (more common)Semipermeable silicone polymer shell; smooth or textured outer surface; silent rupture common
SalineMore radiolucent; has a valve (fluid can be added/removed); rupture clinically evident (deflates)

Implant Shell (“Silicone Sequences” on MRI)

  • Shell = elastomer cell/envelope/membrane = solid silicone polymer
  • Can be smooth or textured outer surface (theory: texturing reduces implant rotation and capsular contracture)
  • Cannot tell on imaging whether textured or smooth

Lumen Types

  • Single lumen: most common
  • Double lumen: inner lumen (silicone) + outer lumen (saline); also silicone-silicone double lumen
    • Can be seen as silicone-silicone; outer lumen appears radiolucent

Implant Position

PositionDescription
Retroglandular/SubglandularAnterior to pectoralis, behind glandular tissue
PrepectoralAnterior to the pectoralis (same as retroglandular/subglandular)
Subpectoral/Retropectoral/SubmuscularPosterior to pectoralis major

Tissue Expanders

  • Expander implant has a metal valve (saline added over time)
  • May not be MRI compatible or may cause too much artifact

Direct Injection Materials

SubstanceImaging Appearance
Silicone injectionsDense masses on mammo, some with peripheral calcs and/or fat necrosis areas
Paraffin injectionsInitially masses representing fluid collections; later masses representing parafffinomas with calcs and AD
Polyacrylamide gelVariable

The Fibrous Capsule

  • When implant is placed → inflammatory reaction → forms fibrous capsule
  • Capsule has a smooth inner surface + creates potential space (between fibrous capsule and implant shell)
  • Fluid can be seen in this space
  • Calcifications often develop within the capsule

Implant Complications

1. Capsular Contracture

  • Most common complication of breast implants
  • Most common in silicone implants in a subglandular location
  • Clinical diagnosis (NOT imaging diagnosis)
  • Fibrous capsule contracts around implant → breast becomes hard and implant’s movement is limited
  • In severe contracture: implant may not be able to be displaced for imaging → usually need to take out the implant and capsule to fix

2. Gel Bleed

  • Silicone molecules can pass through the intact semipermeable membrane shell without rupture
  • Gel can coat the exterior surface of the implant shell
  • Can travel to lymph nodes even without rupture
  • May or may not be symptomatic

3. Implant Rupture

  • Main predisposing factor = age of the implant
  • Can be spontaneous or from external source
  • Rupture during mammography is rare

Saline Implant Rupture:

  • Obvious clinically (breast deflates)
  • Shell is collapsed on mammography

Silicone Implant Rupture — Two Types:

Intracapsular Rupture

  • Implant shell is disrupted but silicone is still contained by the fibrous capsule
  • Patients usually asymptomatic
  • Not apparent on clinical exam or mammography
  • US: NOT very sensitive or specific; finding suggestive = multiple parallel echogenic lines within sonolucent silicone = “stepladder sign”
  • MRI is the most sensitive and specific modality

MRI Signs of Intracapsular Rupture:

SignDescription
Linguine signCurvilinear low intensity signal within implant = collapsed elastomer shell floating in silicone, contained by fibrous capsule
Subcapsular line signSilicone has leaked out of the ruptured shell but shell has not collapsed; silicone on BOTH surfaces of ruptured shell
Inverted teardrop/noose/keyhole signSilicone leakage within a fold of the shell (indicates rupture)
Radial foldsNORMAL — do NOT indicate rupture; contiguous with shell; thicker than intracapsular rupture (double layer of shell)

Pitfall

Radial folds are NORMAL — don’t mistake for intracapsular rupture. Lines of a radial fold are thicker than the collapsed shell in intracapsular rupture (radial folds = double layer of shell). The shell can fold into the implant and have long, complex folds with the shell still intact. Must be contiguous with the shell.

Extracapsular Rupture

  • Silicone has leaked outside the fibrous capsule
  • Usually not a hard diagnosis on any modality
  • Silicone is higher density than breast parenchyma on mammo
  • Follow contour of implant → look for abnormalities or globular/linear silicone tracking outside fibrous capsule
  • Silicone granulomas can form in breast tissue; silicone can extend into ducts
  • US appearance: “snowstorm” appearance (classic); but may present atypically as hypoechoic regions, complex cystic lesion, or shadowing mass
  • MRI: extracapsular silicone has low T1 signal on fat sat T1 and high signal on water-suppressed T2

4. Contour Irregularities

  • Bulge: focal protrusion of implant within intact fibrous capsule (capsule not disrupted)
  • Herniation: portion of implant extends through a defect in the fibrous capsule
    • Opposite of intracapsular rupture (implant intact but fibrous capsule disrupted)
    • May present as palpable mass
  • Mammography alone cannot differentiate bulge from herniation and cannot exclude rupture

Peri-Implant Fluid

  • Small amount adjacent to implant is normal
  • Large or increasing amounts may be due to:
    • Implant rupture, infection, localized/generalized edema, BIA-ALCL, inflammatory carcinoma
    • Hematoma, seroma, mastitis, abscess (in early post-placement period)

Imaging of Women with Implants

Mammography

  • Sensitivity reduced: 45% in women with implants vs. 66% in women without
  • Perform: CC and MLO implant-displaced views + non-displaced views
  • Subpectoral implants are easiest to displace
  • Implants may obscure between 22–83% of breast tissue

Ultrasound for Rupture

  • Sensitivity: 73.7%, Specificity: 87.8%
  • First-line for BIA-ALCL evaluation

MRI for Rupture

  • Most sensitive and specific modality
  • Silicone-specific sequences (suppress fat AND water → only silicone is bright)

Special Implant Issues

Silicone Granulomas

  • Usually high density on mammo
  • May be circumscribed or indistinct
  • Most often identifiable as silicone, but in some cases suspicious for malignancy on mammo (if less dense)

Explantation Consequences

  • Scarring and fat necrosis can produce a mass-like appearance
  • Fibrous capsule often calcifies → if not completely removed, residual calcs may look suspicious
  • Benign palpable findings related to implant: implant fold, valve, implant bulge or herniation, dense free silicone, dense silicone granuloma, dense silicone-containing lymph node, oil cysts, characteristically benign calcs (dystrophic, lucent-centered)

Saline Implant “Baffling”

  • Two lumens and a series of shells of increasing size nested together
  • Unusual appearance — don’t mistake for pathology

Acellular Dermal Matrix (ADM)

  • Surgical mesh of human or animal skin with cells removed (only collagen supporting structures remain)
  • Creates artificial internal soft tissue support
  • Higher complication rate than implant alone
  • Better cosmesis; may prevent malpositioning and capsular contracture

2022 FDA Breast Implant Guidelines

  • First screening exam: 5 years after implantation
  • Subsequent: every 2–3 years
  • Can use US or MRI for screening

Breast Implant Illness Syndrome (BII)

  • Symptoms: arthralgias, fatigue, hair loss, skin changes, lethargy
  • No specific imaging or lab tests
  • Explantation may or may not improve symptoms